STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1148PFAM: Radical SAM domain protein; KEGG: nca:Noca_1430 radical SAM domain-containing protein. (375 aa)    
Predicted Functional Partners:
Afer_1843
PFAM: Chlorite dismutase; KEGG: ttj:TTHA1714 putative heme peroxidase.
  
 
 0.917
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
  
 
 0.915
ctaB
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
     
  0.900
Afer_0251
TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: sus:Acid_3181 uroporphyrinogen-III C- methyltransferase / uroporphyrinogen-III synthase; Belongs to the precorrin methyltransferase family.
  
 0.842
Afer_0728
PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; Rhodanese domain protein; SMART: Rhodanese domain protein; KEGG: mxa:MXAN_2588 molybdopterin biosynthesis protein MoeB.
  
  
 0.557
Afer_1041
L-lactate dehydrogenase (cytochrome); PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; KEGG: sen:SACE_5887 L-lactate dehydrogenase.
  
  
 0.536
Afer_1191
KEGG: npu:Npun_F1553 diguanylate cyclase with PAS/PAC and GAF sensors; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; SMART: GGDEF domain containing protein.
     
 0.477
pheT
KEGG: ade:Adeh_1971 phenylalanyl-tRNA synthetase beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit.
     
 0.448
Afer_1451
Cyclic nucleotide-binding protein; KEGG: mse:Msed_0469 hypothetical protein.
 
  
 0.414
Afer_1934
KEGG: bvi:Bcep1808_7294 tungstate/molybdate binding protein.
 
  
 0.411
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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