Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1149TIGRFAM: acetoacetyl-CoA synthase; PFAM: AMP-dependent synthetase and ligase; KEGG: mgi:Mflv_3863 acetoacetyl-CoA synthase. (654 aa)    
Predicted Functional Partners:
Afer_1146
PFAM: pyruvate carboxyltransferase; KEGG: fre:Franean1_3719 pyruvate carboxyltransferase.
 
 0.940
Afer_0106
KEGG: fal:FRAAL5910 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.919
Afer_0261
TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; KEGG: tfu:Tfu_0436 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.919
Afer_0222
PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: fre:Franean1_1037 3-hydroxybutyryl-CoA dehydrogenase, 3-hydroxyacyl-CoA dehydrogenase.
  
 
 0.912
Afer_1375
PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: ace:Acel_0147 3-hydroxyacyl-CoA dehydrogenase.
  
 
 0.912
Afer_1527
PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: nca:Noca_4392 3-hydroxybutyryl-CoA dehydrogenase.
  
 
 0.912
Afer_1150
Hypothetical protein.
       0.773
Afer_1151
PFAM: AMP-dependent synthetase and ligase; KEGG: sen:SACE_6960 acyl-CoA synthetase.
 
0.749
Afer_1152
TIGRFAM: glycine oxidase ThiO; PFAM: FAD dependent oxidoreductase; KEGG: saq:Sare_4279 glycine oxidase ThiO.
  
  
 0.502
Afer_1154
Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
       0.499
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.