STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1156KEGG: afe:Lferr_2664 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; SMART: GGDEF domain containing protein; EAL domain protein. (626 aa)    
Predicted Functional Partners:
Afer_1401
Diguanylate phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: azo:azo1486 conserved hypothetical signaling protein.
 
  
 0.795
Afer_0022
Diguanylate phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: bln:Blon_0041 hypothetical protein.
 
  
 0.793
Afer_1469
KEGG: eba:ebA6041 signal transducer protein; TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein.
 
 
0.571
Afer_1995
TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: afe:Lferr_2531 ammonium transporter.
 
      0.533
Afer_1155
KEGG: afw:Anae109_1765 phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1.
  
    0.519
Afer_0224
Diguanylate cyclase; KEGG: xca:xccb100_3008 putative sensor protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein.
 
 
 0.483
Afer_1191
KEGG: npu:Npun_F1553 diguanylate cyclase with PAS/PAC and GAF sensors; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; SMART: GGDEF domain containing protein.
 
0.458
Afer_1152
TIGRFAM: glycine oxidase ThiO; PFAM: FAD dependent oxidoreductase; KEGG: saq:Sare_4279 glycine oxidase ThiO.
       0.445
Afer_1153
TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: stp:Strop_3887 thiamine biosynthesis protein ThiS.
       0.445
Afer_1154
Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
       0.445
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.