STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1171PFAM: major facilitator superfamily MFS_1; KEGG: mva:Mvan_5862 major facilitator superfamily transporter. (424 aa)    
Predicted Functional Partners:
Afer_1172
Transcriptional regulator, ArsR family; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; Rhodanese domain protein; KEGG: rha:RHA1_ro11220 ArsR family transcriptional regulator.
 
  
 0.921
Afer_1173
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: smd:Smed_5362 two component transcriptional regulator, winged helix family.
       0.648
Afer_1174
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: smd:Smed_5361 osmosensitive K+ channel signal transduction histidine kinase.
       0.648
Afer_1170
KEGG: ckl:CKL_3030 hypothetical protein.
       0.487
Afer_1175
Osmosensitive K channel signal transduction histidine kinase, sensor subunit KdpD; PFAM: Osmosensitive K channel His kinase sensor; UspA domain protein; KEGG: nfa:nfa15690 putative two-component system sensor kinase.
       0.483
Afer_0282
Hypothetical protein; KEGG: rha:RHA1_ro01864 mycothiol-dependent maleylpyruvate isomerase.
  
     0.453
Afer_0121
KEGG: afe:Lferr_1387 carboxysome structural protein CsoS2.
  
     0.435
Afer_1582
KEGG: fal:FRAAL3631 hypothetical protein.
  
     0.435
Afer_1014
PFAM: beta-lactamase domain protein; KEGG: nca:Noca_2937 beta-lactamase domain- containing protein.
  
 0.425
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.