Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1180PFAM: major facilitator superfamily MFS_1; KEGG: nca:Noca_3966 major facilitator transporter. (418 aa)    
Predicted Functional Partners:
Afer_1181
PFAM: amino acid permease-associated region; KEGG: afe:Lferr_0867 amino acid permease-associated region.
       0.515
Afer_0606
KEGG: fra:Francci3_2206 hypothetical protein.
  
     0.494
Afer_1195
KEGG: scl:sce0507 hypothetical protein.
 
    0.412
Afer_0776
PFAM: protein of unknown function DUF664; KEGG: sco:SCO1340 hypothetical protein.
  
     0.408
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.