STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1232PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sen:SACE_3786 enoyl-(acyl carrier protein) reductase. (257 aa)    
Predicted Functional Partners:
Afer_1085
PFAM: Acyl transferase; KEGG: bsu:BSU15900 acyl-carrier-protein S- malonyltransferase.
 
  
 0.932
Afer_1089
PFAM: Beta-ketoacyl synthase; KEGG: drm:Dred_2070 beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
  
 0.930
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 
 0.883
fabH
3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
  
 0.881
acpP-2
Phosphopantetheine-binding; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
  
 
 0.844
Afer_1231
PFAM: NADP oxidoreductase coenzyme F420-dependent; KEGG: fra:Francci3_3151 reduced coenzyme F420:NADP oxidoreductase.
       0.611
Afer_1230
Cysteine--tRNA ligase; PFAM: Cysteinyl-tRNA synthetase class Ia; tRNA synthetase class I (M); KEGG: sma:SAV_6647 cysteinyl-tRNA synthetase.
       0.609
Afer_1728
PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; KEGG: rxy:Rxyl_1380 3-hydroxyacyl-[acyl-carrier- protein] dehydratase.
 
  
 0.577
Afer_1233
Hypothetical protein; KEGG: predicted gene, 100039767.
       0.574
Afer_1228
PFAM: histidine triad (HIT) protein; KEGG: sus:Acid_4300 histidine triad (HIT) protein.
       0.573
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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