STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sepFProtein of unknown function DUF552; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. (179 aa)    
Predicted Functional Partners:
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.993
Afer_1237
PFAM: protein of unknown function YGGT; KEGG: azc:AZC_3317 hypothetical protein.
  
  
 0.962
Afer_1239
PFAM: alanine racemase domain protein; KEGG: afw:Anae109_1365 alanine racemase domain- containing protein.
  
  
 0.961
Afer_1236
PFAM: DivIVA family protein; KEGG: nfa:nfa17740 hypothetical protein.
 
  
 0.916
Afer_1240
PFAM: protein of unknown function DUF152; KEGG: rxy:Rxyl_1488 protein of unknown function DUF152.
  
  
 0.873
Afer_1246
PFAM: cell cycle protein; KEGG: nfa:nfa17650 putative cell division protein; Belongs to the SEDS family.
     
 0.752
Afer_1245
Undecaprenyldiphospho-muramoylpentapeptidebeta-N -acetylglucosaminyltransferase; PFAM: Glycosyltransferase 28 domain; glycosyl transferase family 28; KEGG: pzu:PHZ_c2323 UDP-N-acetylglucosamine--N- acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N- acetylglucosamine transferase.
     
 0.708
murC
UDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
     
 0.695
Afer_1250
Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerization domain; KEGG: ace:Acel_1004 peptidoglycan glycosyltransferase.
     
 0.695
mraZ
PFAM: protein of unknown function UPF0040; KEGG: cth:Cthe_0982 MraZ protein; Belongs to the MraZ family.
 
   
 0.679
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.