Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1257PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; KEGG: hya:HY04AAS1_1111 peptidase S11 D-alanyl-D- alanine carboxypeptidase 1; Belongs to the peptidase S11 family. (414 aa)    
Predicted Functional Partners:
Afer_0769
Penicillin-binding protein 2; KEGG: fre:Franean1_5266 peptidoglycan glycosyltransferase; TIGRFAM: penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerization domain.
 
 
 0.927
Afer_0089
PFAM: penicillin-binding protein transpeptidase; KEGG: ace:Acel_0020 peptidoglycan glycosyltransferase.
  
 
 0.923
Afer_1250
Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerization domain; KEGG: ace:Acel_1004 peptidoglycan glycosyltransferase.
  
 
 0.923
Afer_0649
PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; KEGG: sco:SCO4439 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
  
  
 
0.919
Afer_1256
Hypothetical protein.
       0.540
Afer_0830
PFAM: glycosyl transferase group 1; KEGG: nca:Noca_1551 hypothetical protein.
 
   
 0.413
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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