Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1266Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (241 aa)    
Predicted Functional Partners:
Afer_0471
PFAM: Polyprenyl synthetase; KEGG: saq:Sare_3478 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
 
 0.966
Afer_0630
PFAM: phosphatidate cytidylyltransferase; KEGG: sth:STH1497 phosphatidate cytidylyltransferase; Belongs to the CDS family.
  
 0.963
dxr
1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.
  
  
 0.937
frr
Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.
 
  
 0.856
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
  
  
 0.852
Afer_0634
prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
  
  
 0.833
Afer_0469
PFAM: Squalene/phytoene synthase; KEGG: saq:Sare_4931 squalene/phytoene synthase.
   
 
 0.824
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
  
 0.791
Afer_1267
PFAM: Domain of unknown function DUF1794; KEGG: cef:CE1476 hypothetical protein.
       0.783
glyQS
glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family.
     
 0.779
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.