Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Afer_1285KEGG: fre:Franean1_3861 protein tyrosine/serine phosphatase. (289 aa)    
Predicted Functional Partners:
Afer_0375
KEGG: fre:Franean1_6082 proton-translocating NADH- quinone oxidoreductase, chain M; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I).
    
 
 0.774
Afer_1283
Hypothetical protein.
       0.762
Afer_1284
Hypothetical protein; KEGG: rso:RS05070 putative hemagglutinin/hemolysin- related protein.
       0.762
Afer_1282
KEGG: hypothetical protein.
       0.557
Afer_1281
Hypothetical protein.
       0.457
Afer_1286
TIGRFAM: acetate/CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: ace:Acel_1984 acetyl-coenzyme A synthetase.
  
    0.437
nuoB
NADH-quinone oxidoreductase, B subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
    
   0.432
Afer_1287
PFAM: GPR1/FUN34/yaaH family protein; KEGG: pth:PTH_2591 hypothetical protein.
       0.418
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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