STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1304KEGG: ace:Acel_1839 dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS. (281 aa)    
Predicted Functional Partners:
Afer_1909
TIGRFAM:2-amino-4-hydroxy-6- hydroxymethyldihydropter idinepyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin- pyrophosphokinase HPPK; KEGG: dra:DR_0170 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase.
 
 0.998
Afer_0764
TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase middle domain protein; KEGG: dra:DR_2575 folyl-polyglutamate synthetase.
 
 0.989
Afer_1910
PFAM: dihydroneopterin aldolase; KEGG: rxy:Rxyl_2579 dihydroneopterin aldolase.
  
 
 0.976
Afer_1911
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
  
  
0.921
Afer_1912
PFAM: GTP cyclohydrolase I; KEGG: paa:Paes_0859 GTP cyclohydrolase I; Belongs to the GTP cyclohydrolase I family.
 
  
 0.878
Afer_1305
TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: cau:Caur_0205 thioredoxin domain-containing protein.
  
   0.827
Afer_1303
KEGG: rha:RHA1_ro01286 DNA polymerase III delta subunit.
       0.808
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
  
 0.574
Afer_1306
PFAM: aldo/keto reductase; KEGG: nca:Noca_0658 aldo/keto reductase.
       0.553
Afer_1307
PFAM: alpha/beta hydrolase fold; KEGG: met:M446_4655 3-oxoadipate enol-lactonase.
       0.553
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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