Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1326PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: msm:MSMEG_2682 transcriptional regulator. (264 aa)    
Predicted Functional Partners:
Afer_1409
Transcriptional regulator, GntR family; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: sgr:SGR_1276 GntR family transcriptional regulator.
  
  
 0.707
Afer_1614
Transcriptional regulator, GntR family; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: dsy:DSY4747 hypothetical protein.
  
  
 0.699
Afer_0216
Transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; GntR domain protein; SMART: regulatory protein GntR HTH; KEGG: dau:Daud_0059 GntR family transcriptional regulator.
 
  
 0.620
Afer_2024
PFAM: regulatory protein IclR; Transcriptional regulator IclR; SMART: regulatory protein IclR; KEGG: cgt:cgR_2273 hypothetical protein.
 
  
 0.603
Afer_0274
Transcriptional regulator, XRE family; PFAM: Cupin 2 conserved barrel domain protein; helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: art:Arth_0847 transcriptional regulator, XRE family with cupin sensor.
 
  
 0.600
Afer_1325
PFAM: amino acid permease-associated region; KEGG: mmi:MMAR_2052 amino acid transporter.
       0.531
Afer_1324
PFAM: peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin; KEGG: sco:SCO2328 dipeptidase.
       0.418
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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