STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1332KEGG: nca:Noca_3918 LacI family transcription regulator; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI. (377 aa)    
Predicted Functional Partners:
Afer_1988
PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: ace:Acel_1078 glutamate synthase (NADH) large subunit.
    
 
 0.914
Afer_1331
PFAM: extracellular solute-binding protein family 1; KEGG: sen:SACE_6262 putative ABC transporter substrate-binding protein.
 
  
 0.680
Afer_0993
Monosaccharide-transporting ATPase; PFAM: inner-membrane translocator; KEGG: rxy:Rxyl_0947 inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family.
 
  
 0.660
Afer_0994
PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: acr:Acry_1366 periplasmic binding protein/LacI transcriptional regulator.
 
  
 0.621
Afer_1409
Transcriptional regulator, GntR family; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: sgr:SGR_1276 GntR family transcriptional regulator.
  
   
 0.608
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
    
   0.596
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
   0.596
Afer_1328
PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: bra:BRADO0511 alpha-glucosidase.
 
  
 0.575
Afer_1329
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sen:SACE_6264 putative multiple sugar transport system permease protein.
 
   
 0.533
Afer_1327
PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: tfu:Tfu_1763 ABC-type sugar transport systems ATPase components; Belongs to the ABC transporter superfamily.
 
  
 0.529
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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