STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1346Propionyl-CoA carboxylase; PFAM: carboxyl transferase; KEGG: saq:Sare_0033 propionyl-CoA carboxylase. (508 aa)    
Predicted Functional Partners:
Afer_0730
PFAM: Carbamoyl-phosphate synthase L chain ATP- binding; biotin carboxylase domain protein; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: kra:Krad_3912 carbamoyl-phosphate synthase L chain ATP-binding.
 
 0.993
Afer_1032
PFAM: Carbamoyl-phosphate synthase L chain ATP- binding; biotin carboxylase domain protein; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; phosphoribosylglycinamide synthetase; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: fal:FRAAL1668 acetyl-/propionyl-coenzyme A carboxylase alpha chain.
 
 0.993
der
Small GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
       0.748
Afer_1348
PFAM: protein of unknown function DUF512; KEGG: syw:SYNW2188 Fe-S oxidoreductase.
       0.748
Afer_1344
PFAM: beta-lactamase domain protein; KEGG: sma:SAV_6616 polyketide cyclase.
  
    0.663
Afer_1146
PFAM: pyruvate carboxyltransferase; KEGG: fre:Franean1_3719 pyruvate carboxyltransferase.
 
 0.658
Afer_1345
Hypothetical protein.
       0.651
Afer_0731
TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; KEGG: rpb:RPB_3299 biotin--acetyl-CoA-carboxylase ligase.
  
 
 0.623
Afer_1033
PFAM: protein of unknown function DUF1446; KEGG: mjl:Mjls_3217 hypothetical protein.
  
  
 0.587
Afer_0104
TIGRFAM: methylmalonyl-CoA epimerase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: pho:PH0272 hypothetical protein.
  
 
 0.566
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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