Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1384PFAM: metallophosphoesterase; KEGG: nca:Noca_3235 metallophosphoesterase. (546 aa)    
Predicted Functional Partners:
Afer_1383
PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: mva:Mvan_5739 ABC transporter-related protein; Belongs to the ABC transporter superfamily.
       0.785
Afer_1380
KEGG: msm:MSMEG_6524 ABC polyamine/opine/phosphonate transporter, periplasmic ligand binding protein.
       0.781
Afer_1382
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bpy:Bphyt_0516 binding-protein-dependent transport systems inner membrane component.
       0.781
Afer_1381
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: acr:Acry_0983 binding-protein-dependent transport systems inner membrane component.
       0.778
Afer_0050
PFAM: Secreted repeat of unknown function; KEGG: ace:Acel_0027 hypothetical protein.
  
     0.536
Afer_0809
KEGG: rha:RHA1_ro01772 hypothetical protein.
  
     0.534
Afer_0071
Hypothetical protein; KEGG: fal:FRAAL5406 glycine-rich cell wall structural protein precursor (partial match).
  
     0.506
Afer_1410
PFAM: permease for cytosine/purines uracil thiamine allantoin; KEGG: acr:Acry_2484 permease for cytosine/purines, uracil, thiamine, allantoin; Belongs to the purine-cytosine permease (2.A.39) family.
  
     0.503
Afer_1784
PFAM: pyridoxamine 5'-phosphate oxidase-related FMN- binding; KEGG: mab:MAB_3296 hypothetical protein.
  
     0.486
Afer_0083
PFAM: Secreted repeat of unknown function; KEGG: ace:Acel_0027 hypothetical protein.
  
     0.475
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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