Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1400KEGG: ace:Acel_1702 secreted protein. (364 aa)    
Predicted Functional Partners:
Afer_0648
PFAM: cell division FtsK/SpoIIIE; SMART: AAA ATPase; KEGG: ace:Acel_1501 cell division FtsK/SpoIIIE.
  
 
 0.800
Afer_1631
PFAM: protein of unknown function DUF255; KEGG: nfa:nfa48210 hypothetical protein.
    
   0.719
Afer_1401
Diguanylate phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: azo:azo1486 conserved hypothetical signaling protein.
     
 0.646
Afer_1402
Diguanylate phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: fal:FRAAL5844 hypothetical protein.
     
 0.646
Afer_1507
PFAM: SMC domain protein; KEGG: sen:SACE_6071 chromosome segregation ATPase.
   
 
 0.558
Afer_1399
PFAM: transposase IS4 family protein; KEGG: mva:Mvan_4071 transposase, IS4 family protein.
       0.532
Afer_0811
Endothelin-converting enzyme 1; PFAM: peptidase M13; peptidase M13 neprilysin; KEGG: lxx:Lxx01010 metallopeptidase.
  
    0.485
Afer_1822
Hypothetical protein; KEGG: fal:FRAAL5121 putative integral membrane protein.
  
     0.403
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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