STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1409Transcriptional regulator, GntR family; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: sgr:SGR_1276 GntR family transcriptional regulator. (252 aa)    
Predicted Functional Partners:
Afer_0274
Transcriptional regulator, XRE family; PFAM: Cupin 2 conserved barrel domain protein; helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: art:Arth_0847 transcriptional regulator, XRE family with cupin sensor.
 
  
 0.699
Afer_1326
PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: msm:MSMEG_2682 transcriptional regulator.
  
    0.696
Afer_1332
KEGG: nca:Noca_3918 LacI family transcription regulator; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI.
  
   
 0.608
Afer_0169
KEGG: sgr:SGR_2421 LacI family transcriptional regulator; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI.
  
   
 0.605
hutU
Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
  
  
 0.595
Afer_1415
Imidazolonepropionase; KEGG: mmr:Mmar10_1604 imidazolonepropionase; TIGRFAM: imidazolonepropionase; PFAM: amidohydrolase; Amidohydrolase 3.
  
  
 0.593
Afer_0995
Transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: cmi:CMM_2841 LacI family transcriptional regulator.
  
   
 0.583
Afer_1413
PFAM: amidohydrolase; KEGG: kra:Krad_4451 N-formimino-L-glutamate deiminase.
  
  
 0.573
Afer_1408
KEGG: bba:Bd2784 aconitate hydratase; TIGRFAM: aconitate hydratase; PFAM: aconitate hydratase domain protein.
       0.563
Afer_0346
KEGG: saq:Sare_3145 transcriptional regulator, TrmB.
   
  
 0.557
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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