STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (552 aa)    
Predicted Functional Partners:
hutH
KEGG: eba:ebA5742 histidine ammonia-lyase; TIGRFAM: histidine ammonia-lyase; PFAM: phenylalanine/histidine ammonia-lyase.
 
 0.999
Afer_1415
Imidazolonepropionase; KEGG: mmr:Mmar10_1604 imidazolonepropionase; TIGRFAM: imidazolonepropionase; PFAM: amidohydrolase; Amidohydrolase 3.
 
 0.999
Afer_1413
PFAM: amidohydrolase; KEGG: kra:Krad_4451 N-formimino-L-glutamate deiminase.
 
  
 0.906
Afer_1410
PFAM: permease for cytosine/purines uracil thiamine allantoin; KEGG: acr:Acry_2484 permease for cytosine/purines, uracil, thiamine, allantoin; Belongs to the purine-cytosine permease (2.A.39) family.
  
    0.813
Afer_1411
Transcriptional regulator, RpiR family; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: rxy:Rxyl_0574 transcriptional regulator, RpiR family.
       0.809
Afer_1412
KEGG: sgr:SGR_4463 M20/M25/M40 family peptidase; TIGRFAM: amidase, hydantoinase/carbamoylase family; PFAM: peptidase M20.
       0.809
Afer_1409
Transcriptional regulator, GntR family; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: sgr:SGR_1276 GntR family transcriptional regulator.
  
  
 0.595
Afer_0072
PFAM: transcriptional activator domain; KEGG: mva:Mvan_1815 transcriptional regulator.
       0.499
Afer_0273
TIGRFAM: agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: nca:Noca_3382 agmatinase; Belongs to the arginase family.
  
  
 0.466
Afer_1408
KEGG: bba:Bd2784 aconitate hydratase; TIGRFAM: aconitate hydratase; PFAM: aconitate hydratase domain protein.
  
  
 0.447
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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