STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1431PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: fre:Franean1_4169 alcohol dehydrogenase. (400 aa)    
Predicted Functional Partners:
Afer_1430
KEGG: nca:Noca_2000 hypothetical protein.
 
     0.911
Afer_1432
TIGRFAM: HAD-superfamily subfamily IB hydrolase, TIGR01490; PFAM: Male sterility domain; Haloacid dehalogenase domain protein hydrolase; NAD-dependent epimerase/dehydratase; KEGG: fal:FRAAL3759 putative fatty acyl CoA reductase.
 
  
 0.902
Afer_1429
PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; KEGG: fre:Franean1_4167 phospholipid/glycerol acyltransferase.
 
     0.855
Afer_0265
PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: sma:SAV_6448 alcohol dehydrogenase.
  
     0.712
Afer_1433
Hypothetical protein.
       0.609
Afer_0817
KEGG: nfa:nfa40830 putative magnesium chelatase subunit; PFAM: ATPase associated with various cellular activities AAA_5; AAA ATPase central domain protein; von Willebrand factor type A; magnesium chelatase ChlI subunit; SMART: von Willebrand factor type A; AAA ATPase.
   
  
 0.438
Afer_1434
PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: mse:Msed_0866 general substrate transporter.
  
  
 0.437
lipB
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives; Belongs to the LipB family.
     
 0.415
Afer_0094
TIGRFAM: phenylacetic acid degradation protein paaN; PFAM: MaoC domain protein dehydratase; Aldehyde Dehydrogenase; KEGG: nfa:nfa21550 bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase.
  
 
 0.402
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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