STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1431PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: fre:Franean1_4169 alcohol dehydrogenase. (400 aa)    
Predicted Functional Partners:
Afer_1430
KEGG: nca:Noca_2000 hypothetical protein.
 
     0.908
Afer_1432
TIGRFAM: HAD-superfamily subfamily IB hydrolase, TIGR01490; PFAM: Male sterility domain; Haloacid dehalogenase domain protein hydrolase; NAD-dependent epimerase/dehydratase; KEGG: fal:FRAAL3759 putative fatty acyl CoA reductase.
 
  
 0.896
Afer_1429
PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; KEGG: fre:Franean1_4167 phospholipid/glycerol acyltransferase.
 
    0.849
Afer_0265
PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: sma:SAV_6448 alcohol dehydrogenase.
  
     0.712
Afer_1433
Hypothetical protein.
       0.617
Afer_0817
KEGG: nfa:nfa40830 putative magnesium chelatase subunit; PFAM: ATPase associated with various cellular activities AAA_5; AAA ATPase central domain protein; von Willebrand factor type A; magnesium chelatase ChlI subunit; SMART: von Willebrand factor type A; AAA ATPase.
   
  
 0.470
Afer_0166
TIGRFAM: transketolase; fructose-1,6- bisphosphatase, class II; PFAM: GlpX family protein; Transketolase domain protein; Transketolase central region; KEGG: ttj:TTHA0108 transketolase; Belongs to the transketolase family.
  
 
 0.462
ispF
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). Belongs to the IspF family. In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
  
  
 0.440
Afer_1434
PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: mse:Msed_0866 general substrate transporter.
  
  
 0.434
lipB
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives; Belongs to the LipB family.
     
 0.409
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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