Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Afer_1452TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074; KEGG: glo:Glov_1241 transcriptional regulator, BadM/Rrf2 family. (273 aa)    
Predicted Functional Partners:
Afer_0500
Cysteine desulfurase; PFAM: aminotransferase class V; KEGG: ank:AnaeK_1104 aminotransferase class V.
  
  
 0.778
Afer_1450
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dsy:DSY3404 hypothetical protein.
     
 0.594
Afer_0568
TIGRFAM: SUF system FeS assembly protein, NifU family; PFAM: nitrogen-fixing NifU domain protein; KEGG: tth:TTC1374 IscU protein.
  
  
 0.586
Afer_1451
Cyclic nucleotide-binding protein; KEGG: mse:Msed_0469 hypothetical protein.
  
  
 0.577
Afer_1377
PFAM: ferredoxin; Oxidoreductase FAD-binding domain protein; oxidoreductase FAD/NAD(P)-binding domain protein; KEGG: dar:Daro_0368 ferredoxin:oxidoreductase FAD/NAD(P)-binding:oxidoreductase FAD-binding region.
  
  
 0.562
Afer_1021
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; Polysulphide reductase NrfD; KEGG: nca:Noca_2933 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein.
  
  
 0.483
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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