Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1455PFAM: aldo/keto reductase; KEGG: bac:BamMC406_2130 aldo/keto reductase. (322 aa)    
Predicted Functional Partners:
Afer_1306
PFAM: aldo/keto reductase; KEGG: nca:Noca_0658 aldo/keto reductase.
 
     0.595
Afer_0024
PFAM: histone deacetylase superfamily; KEGG: sul:SYO3AOP1_1212 histone deacetylase superfamily.
   
  0.550
Afer_1456
Hypothetical protein; KEGG: bpa:BPP4333 putative integral membrane protein.
       0.512
Afer_1453
Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: cts:Ctha_1302 ferric uptake regulator, Fur family; Belongs to the Fur family.
       0.500
Afer_1454
KEGG: hya:HY04AAS1_0184 hypothetical protein.
       0.494
Afer_1457
PFAM: Methyltransferase type 12; Methyltransferase type 11; KEGG: sco:SCO3340 hypothetical protein.
       0.467
Afer_1458
PFAM: Amidase; KEGG: sen:SACE_2834 secreted amidase.
       0.467
Afer_1459
KEGG: stp:Strop_0704 hypothetical protein.
       0.467
Afer_1460
PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicases; helicase domain protein; KEGG: dau:Daud_0816 DEAD/DEAH box helicase domain- containing protein.
       0.467
Afer_0875
TIGRFAM: MIP family channel protein; PFAM: major intrinsic protein; KEGG: sco:SCO4057 transport integral membrane protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
 
 0.414
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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