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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mshDMycothiol biosynthesis acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol. (310 aa)    
Predicted Functional Partners:
ppk
Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.
      0.872
Afer_1609
PFAM: LmbE family protein; KEGG: sen:SACE_0909 N- acetylglucosaminylphosphatidylinositol deacetylase.
  
   
 0.851
Afer_0835
KEGG: saq:Sare_3891 hypothetical protein.
  
 
   0.787
Afer_1463
PFAM: aminotransferase class V; KEGG: stp:Strop_1799 aminotransferase, class V.
     
 0.726
Afer_1230
Cysteine--tRNA ligase; PFAM: Cysteinyl-tRNA synthetase class Ia; tRNA synthetase class I (M); KEGG: sma:SAV_6647 cysteinyl-tRNA synthetase.
    
 0.680
Afer_0258
KEGG: cef:CE1107 hypothetical protein.
  
     0.678
Afer_0194
PFAM: ATP-dependent Clp protease adaptor protein ClpS; KEGG: rha:RHA1_ro01441 ATP-dependent Clp protease adaptor protein ClpS; Belongs to the ClpS family.
  
     0.615
Afer_0241
Putative two component transcriptional regulator, winged helix family; PFAM: transcriptional regulator domain protein; KEGG: sma:SAV_4042 two-component system response regulator.
    
 0.604
Afer_0259
KEGG: kra:Krad_1834 hypothetical protein.
  
     0.592
mltG
Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.
   
    0.586
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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