STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1473KEGG: sus:Acid_7587 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein. (327 aa)    
Predicted Functional Partners:
Afer_1733
PFAM: alpha/beta hydrolase fold; KEGG: fre:Franean1_2175 alpha/beta hydrolase fold.
  
     0.649
Afer_1023
KEGG: afw:Anae109_1828 hypothetical protein.
  
     0.590
Afer_0114
Flagellar hook-associated 2 domain protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
  
     0.576
purK
Phosphoribosylaminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR); Belongs to the PurK/PurT family.
       0.545
purE
Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
       0.545
Afer_1476
KEGG: saq:Sare_3286 hypothetical protein.
       0.545
Afer_0256
PFAM: metallophosphoesterase; KEGG: pzu:PHZ_c0307 3',5'-cyclic-nucleotide phosphodiesterase.
  
     0.535
Afer_1708
PFAM: cytochrome c oxidase subunit II; KEGG: gvi:glr0739 cytochrome c oxidase subunit II.
 
  
 0.535
Afer_0577
KEGG: oih:OB1441 hypothetical protein.
  
     0.530
Afer_1451
Cyclic nucleotide-binding protein; KEGG: mse:Msed_0469 hypothetical protein.
  
     0.515
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.