STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1492PFAM: nitrogen-fixing NifU domain protein; KEGG: sat:SYN_02452 NifU-like domain-containing protein. (109 aa)    
Predicted Functional Partners:
Afer_1493
PFAM: Enoyl-CoA hydratase/isomerase; KEGG: sma:SAV_3829 enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
   
   0.786
Afer_1494
KEGG: mva:Mvan_4307 hypothetical protein.
       0.773
Afer_0313
TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: fal:FRAAL1187 succinate dehydrogenase iron- sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 
 0.668
Afer_0500
Cysteine desulfurase; PFAM: aminotransferase class V; KEGG: ank:AnaeK_1104 aminotransferase class V.
 
 
 0.642
ppa
Inorganic diphosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
       0.636
Afer_0240
TIGRFAM: iron-sulfur cluster assembly accessory protein; PFAM: HesB/YadR/YfhF-family protein; KEGG: cja:CJA_0888 HesB/YadR/YfhF family protein; Belongs to the HesB/IscA family.
  
 
 0.627
nuoI
NADH-quinone oxidoreductase, chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
   
  
 0.624
ilvD
KEGG: nfa:nfa11740 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family.
  
 
 0.603
lipB
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives; Belongs to the LipB family.
  
 
 0.537
Afer_0568
TIGRFAM: SUF system FeS assembly protein, NifU family; PFAM: nitrogen-fixing NifU domain protein; KEGG: tth:TTC1374 IscU protein.
  
 
 0.517
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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