Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1517PFAM: Dak phosphatase; KEGG: nca:Noca_3286 Dak phosphatase. (539 aa)    
Predicted Functional Partners:
Afer_0028
TIGRFAM: degV family protein; PFAM: DegV family protein; KEGG: hau:Haur_0363 DegV family protein.
 
 0.995
recG
DEAD/DEAH box helicase domain protein; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.
  
    0.922
Afer_1515
TIGRFAM: methyltransferase; PFAM: Protein of unknown function methylase putative; KEGG: aeh:Mlg_2656 putative methyltransferase.
 
     0.858
Afer_1513
KEGG: ace:Acel_1577 hypothetical protein.
 
     0.758
Afer_1512
PFAM: protein of unknown function DUF177; KEGG: nca:Noca_3282 hypothetical protein.
 
     0.756
coaD
Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
 
     0.750
rpmB
TIGRFAM: ribosomal protein L28; PFAM: ribosomal protein L28; KEGG: fre:Franean1_1131 50S ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
       0.650
Afer_1507
PFAM: SMC domain protein; KEGG: sen:SACE_6071 chromosome segregation ATPase.
 
    0.581
plsX
Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
 
  
 0.560
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
       0.554
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.