STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1525KEGG: ajs:Ajs_2017 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: GGDEF domain containing protein; EAL domain protein. (1167 aa)    
Predicted Functional Partners:
Afer_0022
Diguanylate phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: bln:Blon_0041 hypothetical protein.
 
  
 0.800
Afer_1469
KEGG: eba:ebA6041 signal transducer protein; TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein.
 
 
0.579
Afer_1526
PFAM: acyl-CoA dehydrogenase domain protein; Acyl- CoA dehydrogenase type 2 domain; KEGG: stp:Strop_0934 acyl-CoA dehydrogenase domain- containing protein.
       0.525
Afer_1527
PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: nca:Noca_4392 3-hydroxybutyryl-CoA dehydrogenase.
       0.525
Afer_1523
PFAM: Cytochrome b/b6 domain; KEGG: ace:Acel_1781 hypothetical protein.
       0.506
Afer_1524
KEGG: ace:Acel_1781 hypothetical protein.
       0.506
Afer_1191
KEGG: npu:Npun_F1553 diguanylate cyclase with PAS/PAC and GAF sensors; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; SMART: GGDEF domain containing protein.
 
 
0.474
Afer_0224
Diguanylate cyclase; KEGG: xca:xccb100_3008 putative sensor protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein.
 
 
 0.465
gltX
glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
       0.445
Afer_1470
Diguanylate cyclase; KEGG: cti:RALTA_B0100 putative diguanylate cyclase (GGDEAF) and C-di-GMP phosphodiesterase (EAL domain) with CHASE and PAS domains; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein.
 
 
0.429
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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