Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Afer_1553PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; PASTA domain containing protein; SMART: serine/threonine protein kinase; tyrosine protein kinase; PASTA domain containing protein; KEGG: ace:Acel_0986 serine/threonine protein kinase. (630 aa)    
Predicted Functional Partners:
Afer_0090
PFAM: Stage II sporulation E family protein; Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein; KEGG: nfa:nfa840 putative protein phosphatase.
 
 
 0.983
Afer_0873
PFAM: Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein; KEGG: dra:DR_2513 hypothetical protein.
 
 
 0.983
Afer_0092
FHA domain containing protein; PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein; KEGG: art:Arth_0026 FHA domain containing protein.
 
 
 
 0.959
Afer_1125
FHA domain containing protein; PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein; KEGG: ace:Acel_1226 FHA domain-containing protein.
 
 
 
 0.954
Afer_0091
FHA domain containing protein; PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein; KEGG: cef:CE0038 hypothetical protein.
 
 
 
 0.948
ligA
DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
  
    0.742
Afer_1552
KEGG: prw:PsycPRwf_1743 hypothetical protein.
       0.664
Afer_1236
PFAM: DivIVA family protein; KEGG: nfa:nfa17740 hypothetical protein.
  
 
 0.641
pheT
KEGG: ade:Adeh_1971 phenylalanyl-tRNA synthetase beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit.
  
    0.626
gatB
glutamyl-tRNA(Gln) amidotransferase, B subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.
  
    0.625
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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