STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1553PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; PASTA domain containing protein; SMART: serine/threonine protein kinase; tyrosine protein kinase; PASTA domain containing protein; KEGG: ace:Acel_0986 serine/threonine protein kinase. (630 aa)    
Predicted Functional Partners:
Afer_1125
FHA domain containing protein; PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein; KEGG: ace:Acel_1226 FHA domain-containing protein.
 
 
 
 0.992
Afer_0092
FHA domain containing protein; PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein; KEGG: art:Arth_0026 FHA domain containing protein.
 
 
 
 0.991
Afer_0090
PFAM: Stage II sporulation E family protein; Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein; KEGG: nfa:nfa840 putative protein phosphatase.
 
 0.990
Afer_0873
PFAM: Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein; KEGG: dra:DR_2513 hypothetical protein.
 
 0.990
Afer_0091
FHA domain containing protein; PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein; KEGG: cef:CE0038 hypothetical protein.
 
 
 
 0.989
ligA
DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
  
    0.747
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
  
 0.678
gatB
glutamyl-tRNA(Gln) amidotransferase, B subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.
  
    0.670
pheT
KEGG: ade:Adeh_1971 phenylalanyl-tRNA synthetase beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit.
  
    0.670
Afer_1064
PFAM: protein of unknown function DUF1212; KEGG: rha:RHA1_ro04718 amino acid export carrier protein.
       0.669
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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