STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1572PFAM: band 7 protein; SMART: band 7 protein; KEGG: tpe:Tpen_0832 band 7 protein. (307 aa)    
Predicted Functional Partners:
ftsH
ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family.
   
 0.880
Afer_1844
PFAM: AAA ATPase central domain protein; peptidase M41; SMART: AAA ATPase; KEGG: fre:Franean1_1258 ATPase central domain- containing protein; Belongs to the AAA ATPase family.
   
 0.880
Afer_1571
PFAM: protein of unknown function DUF107; KEGG: cpc:Cpar_0823 protein of unknown function DUF107.
  
    0.830
Afer_1708
PFAM: cytochrome c oxidase subunit II; KEGG: gvi:glr0739 cytochrome c oxidase subunit II.
   
 
 0.657
Afer_1824
Cytochrome c oxidase subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
   
 
 0.657
arc
AAA ATPase central domain protein; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
   
 
 0.639
Afer_0291
TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; Haloacid dehalogenase domain protein hydrolase; cation transporting ATPase domain protein; KEGG: afe:Lferr_2687 ATPase, P-type (transporting), HAD superfamily, subfamily IC.
   
 0.600
Afer_1569
Carbon-monoxide dehydrogenase (acceptor); PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; KEGG: rxy:Rxyl_0112 xanthine dehydrogenase, molybdenum binding subunit apoprotein.
  
    0.558
Afer_2035
PFAM: 60 kDa inner membrane insertion protein; KEGG: rrs:RoseRS_3965 60 kDa inner membrane insertion protein.
  
 
 0.551
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.550
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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