Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1575KEGG: ace:Acel_1132 solute-binding protein. (404 aa)    
Predicted Functional Partners:
Afer_1573
PFAM: inner-membrane translocator; KEGG: saq:Sare_4238 monosaccharide-transporting ATPase; Belongs to the binding-protein-dependent transport system permease family.
 
 
 0.989
Afer_1574
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mva:Mvan_5292 ABC transporter-related protein.
 
 
 0.982
Afer_0994
PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: acr:Acry_1366 periplasmic binding protein/LacI transcriptional regulator.
 
  
 0.841
Afer_0992
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: msm:MSMEG_1372 ABC transporter ATP-binding protein.
 
  
 0.811
Afer_0993
Monosaccharide-transporting ATPase; PFAM: inner-membrane translocator; KEGG: rxy:Rxyl_0947 inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family.
 
   
 0.808
Afer_1577
Histidine kinase; PFAM: ABC transporter related; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; AAA ATPase; KEGG: sgr:SGR_1497 putative ABC transporter ATP- binding protein.
 
  
 0.798
Afer_1736
PFAM: heat shock protein Hsp20; KEGG: rha:RHA1_ro08348 heat shock protein (18 kDa antigen-like protein); Belongs to the small heat shock protein (HSP20) family.
      
 0.618
frr
Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.
      
 0.559
Afer_1576
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: hau:Haur_2262 two component transcriptional regulator.
  
  
 0.530
Afer_0995
Transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: cmi:CMM_2841 LacI family transcriptional regulator.
 
   
 0.452
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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