STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1576Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: hau:Haur_2262 two component transcriptional regulator. (230 aa)    
Predicted Functional Partners:
Afer_1174
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: smd:Smed_5361 osmosensitive K+ channel signal transduction histidine kinase.
 0.983
Afer_1175
Osmosensitive K channel signal transduction histidine kinase, sensor subunit KdpD; PFAM: Osmosensitive K channel His kinase sensor; UspA domain protein; KEGG: nfa:nfa15690 putative two-component system sensor kinase.
 
 0.941
Afer_1173
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: smd:Smed_5362 two component transcriptional regulator, winged helix family.
  
  
 
0.916
Afer_1100
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: bha:BH1945 two-component sensor histidine kinase.
 
 0.880
Afer_0201
Histidine kinase; KEGG: tfu:Tfu_2909 sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein.
 
 0.879
Afer_0702
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: nca:Noca_1614 ATPase domain-containing protein.
 
 0.877
Afer_0557
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: fra:Francci3_0309 periplasmic sensor signal transduction histidine kinase.
 
 0.862
Afer_1577
Histidine kinase; PFAM: ABC transporter related; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; AAA ATPase; KEGG: sgr:SGR_1497 putative ABC transporter ATP- binding protein.
  
 
 0.844
Afer_1081
PFAM: response regulator receiver; ANTAR domain protein; SMART: response regulator receiver; KEGG: fre:Franean1_2035 response regulator receiver/ANTAR domain-containing protein.
  
   
 0.674
Afer_0217
PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: kra:Krad_0325 response regulator receiver protein.
 
 
 0.580
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.