STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1578Hypothetical protein; KEGG: ade:Adeh_2512 UvrD/REP helicase. (753 aa)    
Predicted Functional Partners:
Afer_1579
PFAM: UvrD/REP helicase; KEGG: syf:Synpcc7942_1157 hypothetical protein.
   
   0.824
Afer_1580
Hypothetical protein.
       0.762
Afer_1581
RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: sma:SAV_6582 RNA polymerase sigma factor SigK; Belongs to the sigma-70 factor family. ECF subfamily.
       0.650
Afer_1582
KEGG: fal:FRAAL3631 hypothetical protein.
       0.645
Afer_1577
Histidine kinase; PFAM: ABC transporter related; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; AAA ATPase; KEGG: sgr:SGR_1497 putative ABC transporter ATP- binding protein.
       0.574
Afer_1576
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: hau:Haur_2262 two component transcriptional regulator.
       0.565
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.