STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1605PFAM: Abortive infection protein; KEGG: mtu:Rv0658c integral membrane protein. (253 aa)    
Predicted Functional Partners:
Afer_1607
PFAM: YdjC family protein; KEGG: ttj:TTHB029 hypothetical protein.
 
     0.658
Afer_1603
PFAM: MaoC domain protein dehydratase; KEGG: saq:Sare_0676 dehydratase.
       0.625
Afer_1604
KEGG: ace:Acel_1395 hypothetical protein.
       0.625
ftsH
ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family.
     
 0.562
Afer_0652
TIGRFAM: competence/damage-inducible protein CinA; PFAM: CinA domain protein; molybdopterin binding domain; KEGG: fal:FRAAL5732 competence-inducible (CinA- like) protein; Belongs to the CinA family.
       0.546
atpC
ATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane.
  
     0.524
Afer_1562
PFAM: protein of unknown function DUF501; KEGG: rxy:Rxyl_0915 hypothetical protein.
  
     0.498
ispF
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). Belongs to the IspF family. In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
       0.475
Afer_0192
PFAM: ABC-2 type transporter; KEGG: fre:Franean1_2079 ABC-2 type transporter.
   
  
 0.473
Afer_0300
PFAM: ABC-2 type transporter; KEGG: mta:Moth_2298 daunorubicin resistance ABC transporter membrane protein.
   
  
 0.473
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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