Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1610Hypothetical protein; KEGG: GK23692. (343 aa)    
Predicted Functional Partners:
dnaE2
DNA polymerase III, alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.
       0.705
Afer_1612
KEGG: fal:FRAAL2179 putative DNA-directed DNA polymerase.
       0.705
Afer_1613
KEGG: cur:cur_0403 hypothetical protein.
       0.705
Afer_1614
Transcriptional regulator, GntR family; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: dsy:DSY4747 hypothetical protein.
       0.624
Afer_0506
PFAM: inner-membrane translocator; KEGG: cya:CYA_2478 hydrophobic amino acid ABC transporter permease; Belongs to the binding-protein-dependent transport system permease family.
  
  
 0.620
Afer_0779
PFAM: inner-membrane translocator; KEGG: acr:Acry_2203 inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family.
  
  
 0.620
Afer_1609
PFAM: LmbE family protein; KEGG: sen:SACE_0909 N- acetylglucosaminylphosphatidylinositol deacetylase.
       0.608
Afer_0507
PFAM: inner-membrane translocator; KEGG: csa:Csal_1420 inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family.
  
  
 0.606
Afer_0780
PFAM: inner-membrane translocator; KEGG: acr:Acry_2204 inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family.
  
  
 0.606
Afer_1608
Hypothetical protein; KEGG: csa:Csal_1939 sterol-binding.
       0.603
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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