STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1613KEGG: cur:cur_0403 hypothetical protein. (195 aa)    
Predicted Functional Partners:
Afer_1612
KEGG: fal:FRAAL2179 putative DNA-directed DNA polymerase.
  
  
 0.992
dnaE2
DNA polymerase III, alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.
  
  
 0.904
Afer_1610
Hypothetical protein; KEGG: GK23692.
       0.705
Afer_1614
Transcriptional regulator, GntR family; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: dsy:DSY4747 hypothetical protein.
       0.682
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
       0.562
Afer_1609
PFAM: LmbE family protein; KEGG: sen:SACE_0909 N- acetylglucosaminylphosphatidylinositol deacetylase.
       0.557
Afer_1608
Hypothetical protein; KEGG: csa:Csal_1939 sterol-binding.
       0.554
Afer_1937
PFAM: metallophosphoesterase; KEGG: mbo:Mb1308 hypothetical protein.
      
 0.485
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.