Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1630PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: cur:cur_1752 dehydrogenase related to short- chain alcohol dehydrogenases. (248 aa)    
Predicted Functional Partners:
Afer_1444
PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: nca:Noca_4120 short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
     0.734
Afer_1085
PFAM: Acyl transferase; KEGG: bsu:BSU15900 acyl-carrier-protein S- malonyltransferase.
 
 0.628
Afer_1631
PFAM: protein of unknown function DUF255; KEGG: nfa:nfa48210 hypothetical protein.
       0.557
Afer_1089
PFAM: Beta-ketoacyl synthase; KEGG: drm:Dred_2070 beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 
 0.530
Afer_1629
PFAM: amino acid permease-associated region; KEGG: rso:RS02383 amino acid transporter transmembrane protein.
   
   0.520
Afer_0094
TIGRFAM: phenylacetic acid degradation protein paaN; PFAM: MaoC domain protein dehydratase; Aldehyde Dehydrogenase; KEGG: nfa:nfa21550 bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase.
  
 0.488
Afer_0459
TIGRFAM: IMP dehydrogenase family protein; PFAM: IMP dehydrogenase/GMP reductase; KEGG: rxy:Rxyl_0815 inositol-5-monophosphate dehydrogenase.
   
 0.450
Afer_1232
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sen:SACE_3786 enoyl-(acyl carrier protein) reductase.
 
  
 0.431
Afer_1937
PFAM: metallophosphoesterase; KEGG: mbo:Mb1308 hypothetical protein.
    
 
 0.430
Afer_0270
PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; KEGG: hau:Haur_0337 ABC transporter related.
 
 
 0.425
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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