Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1637PFAM: protein of unknown function DUF1707; KEGG: sco:SCO2893 hypothetical protein. (148 aa)    
Predicted Functional Partners:
Afer_0955
Phage shock protein A, PspA; PFAM: PspA/IM30 family protein; KEGG: ace:Acel_0950 phage shock protein A, PspA.
 
  
 0.824
Afer_0556
PFAM: protein of unknown function DUF1707; KEGG: sco:SCO5045 hypothetical protein.
  
     0.719
Afer_1353
KEGG: ace:Acel_0953 hypothetical protein.
  
     0.611
Afer_0118
KEGG: fal:FRAAL2980 putative ABC transporter transmembrane protein.
  
     0.579
Afer_1638
KEGG: ace:Acel_1054 DNA polymerase III subunit alpha; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: DNA polymerase III alpha subunit; PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; SMART: phosphoesterase PHP domain protein.
       0.536
Afer_1639
PFAM: peptidase S51 dipeptidase E; KEGG: smt:Smal_0740 peptidase S51 dipeptidase E; Belongs to the peptidase S51 family.
       0.536
Afer_1291
PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: fre:Franean1_2773 XRE family transcriptional regulator.
  
     0.516
Afer_1255
PFAM: regulatory protein AsnC/Lrp family; KEGG: sma:SAV_2677 hypothetical protein.
  
     0.514
Afer_0256
PFAM: metallophosphoesterase; KEGG: pzu:PHZ_c0307 3',5'-cyclic-nucleotide phosphodiesterase.
  
     0.499
Afer_1789
PFAM: regulatory protein TetR; KEGG: sgr:SGR_6910 TetR family transcriptional regulator.
  
     0.469
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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