STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1645PFAM: protein of unknown function DUF165; KEGG: kra:Krad_4383 hypothetical protein. (190 aa)    
Predicted Functional Partners:
queF
7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
 
  
 0.927
Afer_1646
PFAM: protein of unknown function DUF6 transmembrane; KEGG: gtn:GTNG_1176 transporter, EamA family.
 
    0.817
Afer_0073
PFAM: peptidase C60 sortase A and B; KEGG: met:M446_5133 peptidase C60 sortase A and B.
  
     0.637
Afer_0463
Hypothetical protein; KEGG: ace:Acel_1450 RND family efflux transporter MFP subunit.
  
     0.578
Afer_1642
Hypothetical protein; KEGG: rha:RHA1_ro04406 amidase.
  
    0.548
Afer_1643
Hypothetical protein.
       0.547
Afer_0236
PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: bur:Bcep18194_B3050 two component transcriptional regulator.
  
     0.523
Afer_1523
PFAM: Cytochrome b/b6 domain; KEGG: ace:Acel_1781 hypothetical protein.
  
     0.507
Afer_1641
PFAM: AMP-dependent synthetase and ligase; KEGG: tac:Ta0769 acetyl-coenzyme A synthetase.
       0.486
Afer_1844
PFAM: AAA ATPase central domain protein; peptidase M41; SMART: AAA ATPase; KEGG: fre:Franean1_1258 ATPase central domain- containing protein; Belongs to the AAA ATPase family.
  
     0.442
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.