STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1725PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: ade:Adeh_2438 radical SAM family protein. (438 aa)    
Predicted Functional Partners:
Afer_1724
KEGG: ank:AnaeK_1423 protein of unknown function DUF201.
 
     0.945
Afer_1726
PFAM: UvrD/REP helicase; HRDC domain protein; KEGG: sen:SACE_1092 ATP-dependent DNA helicase.
  
    0.779
Afer_1723
PFAM: nitrogen-fixing NifU domain protein; KEGG: pcr:Pcryo_2202 HesB/YadR/YfhF.
 
     0.622
Afer_0840
Polyphosphate:AMP phosphotransferase; PFAM: protein of unknown function DUF344; KEGG: mpt:Mpe_A3289 polyphosphate:AMP phosphotransferase.
   
    0.588
Afer_0577
KEGG: oih:OB1441 hypothetical protein.
  
     0.522
ispF
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). Belongs to the IspF family. In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
     
 0.497
Afer_0685
KEGG: rpa:RPA4458 isoprenylcysteine carboxyl methyltransferase.
  
     0.463
Afer_1290
KEGG: ace:Acel_0781 coproporphyrinogen III oxidase, anaerobic; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB.
  
  
 0.441
Afer_0999
Hypothetical protein; KEGG: nca:Noca_3830 ferric reductase domain- containing protein.
  
     0.432
Afer_0226
PFAM: Vitamin K epoxide reductase; SMART: Vitamin K epoxide reductase; KEGG: ace:Acel_2066 vitamin K epoxide reductase.
  
     0.424
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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