STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1728PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; KEGG: rxy:Rxyl_1380 3-hydroxyacyl-[acyl-carrier- protein] dehydratase. (142 aa)    
Predicted Functional Partners:
fabH
3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
  
 0.988
Afer_1089
PFAM: Beta-ketoacyl synthase; KEGG: drm:Dred_2070 beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 
 0.982
Afer_1085
PFAM: Acyl transferase; KEGG: bsu:BSU15900 acyl-carrier-protein S- malonyltransferase.
 
  
 0.956
Afer_1087
PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: ace:Acel_1151 3-oxoacyl-[acyl-carrier- protein] reductase.
 
 0.953
Afer_1057
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: gtn:GTNG_0470 enoyl-(acyl carrier protein) reductase.
 
 0.936
Afer_0377
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: stp:Strop_0725 short-chain dehydrogenase/reductase SDR.
  
 0.927
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 
 0.881
acpP-2
Phosphopantetheine-binding; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
  
 
 0.881
Afer_1727
TIGRFAM: exodeoxyribonuclease III Xth; exodeoxyribonuclease III; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: ace:Acel_1469 exodeoxyribonuclease III.
       0.808
Afer_0730
PFAM: Carbamoyl-phosphate synthase L chain ATP- binding; biotin carboxylase domain protein; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: kra:Krad_3912 carbamoyl-phosphate synthase L chain ATP-binding.
 
  
 0.730
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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