Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1735PFAM: domain of unknown function DUF1731; NAD- dependent epimerase/dehydratase; KEGG: ote:Oter_2666 hypothetical protein. (307 aa)    
Predicted Functional Partners:
Afer_2012
PFAM: deoxyribodipyrimidine photolyase-related protein; DNA photolyase FAD-binding; KEGG: cyb:CYB_1949 deoxyribodipyrimidine photolyase family protein.
      0.686
Afer_1736
PFAM: heat shock protein Hsp20; KEGG: rha:RHA1_ro08348 heat shock protein (18 kDa antigen-like protein); Belongs to the small heat shock protein (HSP20) family.
       0.463
Afer_0913
TIGRFAM: signal peptidase I; PFAM: peptidase S24 and S26 domain protein; KEGG: pth:PTH_1717 signal peptidase I; Belongs to the peptidase S26 family.
   
    0.433
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
  
    0.433
Afer_1741
PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sco:SCO4841 short-chain dehydrogenase.
  
    0.421
Afer_1445
PFAM: PhoU family protein; KEGG: sco:SCO4228 phosphate transport system regulator.
   
    0.417
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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