STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1735PFAM: domain of unknown function DUF1731; NAD- dependent epimerase/dehydratase; KEGG: ote:Oter_2666 hypothetical protein. (307 aa)    
Predicted Functional Partners:
Afer_2012
PFAM: deoxyribodipyrimidine photolyase-related protein; DNA photolyase FAD-binding; KEGG: cyb:CYB_1949 deoxyribodipyrimidine photolyase family protein.
      0.690
lipB
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives; Belongs to the LipB family.
     
 0.590
Afer_1736
PFAM: heat shock protein Hsp20; KEGG: rha:RHA1_ro08348 heat shock protein (18 kDa antigen-like protein); Belongs to the small heat shock protein (HSP20) family.
       0.463
Afer_1732
TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: Transketolase central region; dehydrogenase E1 component; catalytic domain of components of various dehydrogenase complexes; KEGG: ace:Acel_0586 alpha-ketoglutarate decarboxylase.
  
    0.452
Afer_1741
PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sco:SCO4841 short-chain dehydrogenase.
  
    0.416
Afer_0913
TIGRFAM: signal peptidase I; PFAM: peptidase S24 and S26 domain protein; KEGG: pth:PTH_1717 signal peptidase I; Belongs to the peptidase S26 family.
   
    0.400
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.