Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Afer_1741PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sco:SCO4841 short-chain dehydrogenase. (252 aa)    
Predicted Functional Partners:
Afer_1740
PFAM: FAD linked oxidase domain protein; KEGG: sco:SCO4842 oxidoreductase.
 
  
 0.960
Afer_1739
PFAM: UbiA prenyltransferase; KEGG: cdi:DIP2196 phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase; Belongs to the UbiA prenyltransferase family.
 
  
 0.950
Afer_1738
KEGG: lbr:LVIS_2016 hypothetical protein.
       0.632
Afer_1737
PFAM: ABC-1 domain protein; KEGG: fal:FRAAL6034 ABC transporter, ATP-binding protein.
       0.628
Afer_1432
TIGRFAM: HAD-superfamily subfamily IB hydrolase, TIGR01490; PFAM: Male sterility domain; Haloacid dehalogenase domain protein hydrolase; NAD-dependent epimerase/dehydratase; KEGG: fal:FRAAL3759 putative fatty acyl CoA reductase.
     
 0.548
Afer_0094
TIGRFAM: phenylacetic acid degradation protein paaN; PFAM: MaoC domain protein dehydratase; Aldehyde Dehydrogenase; KEGG: nfa:nfa21550 bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase.
     
 0.476
Afer_1736
PFAM: heat shock protein Hsp20; KEGG: rha:RHA1_ro08348 heat shock protein (18 kDa antigen-like protein); Belongs to the small heat shock protein (HSP20) family.
       0.442
Afer_1735
PFAM: domain of unknown function DUF1731; NAD- dependent epimerase/dehydratase; KEGG: ote:Oter_2666 hypothetical protein.
  
    0.421
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
  
 0.413
Afer_1377
PFAM: ferredoxin; Oxidoreductase FAD-binding domain protein; oxidoreductase FAD/NAD(P)-binding domain protein; KEGG: dar:Daro_0368 ferredoxin:oxidoreductase FAD/NAD(P)-binding:oxidoreductase FAD-binding region.
     
 0.409
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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