Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ftsECell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. (231 aa)    
Predicted Functional Partners:
Afer_1760
Protein of unknown function DUF214; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
 
 
 0.999
Afer_0298
PFAM: NLP/P60 protein; KEGG: sgr:SGR_2734 NLP/P60 family secreted protein.
 
 
 0.972
Afer_0191
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: tfu:Tfu_1989 ABC-type multidrug transport system ATPase componen.
 
    
0.911
Afer_0174
KEGG: reh:H16_A1303 ABC-type transporter, ATPase component: PepT family; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; Belongs to the ABC transporter superfamily.
 
    
0.906
Afer_0270
PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; KEGG: hau:Haur_0337 ABC transporter related.
 
     
0.877
Afer_1192
PFAM: NLP/P60 protein; KEGG: ace:Acel_2144 NLP/P60 protein.
 
 
 0.788
secA
Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
     
 0.788
prfB
Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
 
  
 0.728
Afer_1759
KEGG: scl:sce3939 hypothetical protein.
       0.655
Afer_1358
KEGG: cmi:CMM_1979 hypothetical protein.
  
  
 0.622
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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