Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
murAUDP-N-acetylglucosamine1- carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (423 aa)    
Predicted Functional Partners:
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
 
  
 0.992
Afer_1599
PFAM: Nucleotidyl transferase; transferase hexapeptide repeat containing protein; KEGG: tfu:Tfu_0414 UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N- acetyltransferase.
 
  
 0.948
murC
UDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
 
  
 0.883
Afer_1123
PFAM: Nucleotidyl transferase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; transferase hexapeptide repeat containing protein; KEGG: tfu:Tfu_1394 mannose-1-phosphate guanylyltransferase.
  
 
 0.882
murD
UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
 
   
 0.867
Afer_1245
Undecaprenyldiphospho-muramoylpentapeptidebeta-N -acetylglucosaminyltransferase; PFAM: Glycosyltransferase 28 domain; glycosyl transferase family 28; KEGG: pzu:PHZ_c2323 UDP-N-acetylglucosamine--N- acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N- acetylglucosamine transferase.
 
   
 0.856
mraY
phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
 
  
 0.855
Afer_0487
TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; KEGG: sma:SAV_3673 UTP:glucose-1-phosphate uridylyltransferase.
    
 0.851
Afer_1780
TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein; KEGG: saq:Sare_3990 LAO/AO transport system ATPase.
       0.820
Afer_0738
PFAM: Nucleotidyl transferase; KEGG: rxy:Rxyl_1624 nucleotidyl transferase.
    
 0.817
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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