STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1782PFAM: major facilitator superfamily MFS_1; KEGG: scl:sce1439 major facilitator superfamily permease. (491 aa)    
Predicted Functional Partners:
Afer_1783
Carboxymethylenebutenolidase; PFAM: dienelactone hydrolase; BAAT/Acyl-CoA thioester hydrolase; KEGG: scl:sce0062 putative carboxymethylenebutenolidase.
       0.737
murA
UDP-N-acetylglucosamine1- carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
     
 0.654
Afer_1778
KEGG: fal:FRAAL5900 trehalose synthase (maltose alpha-D-glucosyltransferase); TIGRFAM: trehalose synthase; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain.
     
 0.649
Afer_1779
PFAM: Enoyl-CoA hydratase/isomerase; KEGG: sen:SACE_6207 enoyl-CoA hydratase-isomerase; Belongs to the enoyl-CoA hydratase/isomerase family.
       0.648
Afer_1780
TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein; KEGG: saq:Sare_3990 LAO/AO transport system ATPase.
       0.648
Afer_1784
PFAM: pyridoxamine 5'-phosphate oxidase-related FMN- binding; KEGG: mab:MAB_3296 hypothetical protein.
       0.640
Afer_1785
Hypothetical protein.
       0.640
fumC
Fumarate lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
       0.640
Afer_1777
Citrate (pro-3S)-lyase; PFAM: HpcH/HpaI aldolase; KEGG: sgr:SGR_1172 putative lyase; Belongs to the HpcH/HpaI aldolase family.
       0.550
Afer_1843
PFAM: Chlorite dismutase; KEGG: ttj:TTHA1714 putative heme peroxidase.
  
     0.548
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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