STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1828PFAM: cytochrome c oxidase subunit III; KEGG: mjl:Mjls_3302 cytochrome c oxidase, subunit III. (198 aa)    
Predicted Functional Partners:
Afer_1707
PFAM: cytochrome c oxidase subunit I; KEGG: syp:SYNPCC7002_A0726 cytochrome oxidase II large subunit; Belongs to the heme-copper respiratory oxidase family.
 
 0.999
Afer_1708
PFAM: cytochrome c oxidase subunit II; KEGG: gvi:glr0739 cytochrome c oxidase subunit II.
 
 0.999
Afer_1822
Hypothetical protein; KEGG: fal:FRAAL5121 putative integral membrane protein.
 
 
 0.999
Afer_1823
Cytochrome c oxidase, subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
 
 0.999
Afer_1824
Cytochrome c oxidase subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
 
 0.999
Afer_1825
PFAM: Cytochrome b/b6 domain; KEGG: fre:Franean1_1812 cytochrome b/b6 domain- containing protein.
 
 
 0.999
Afer_1826
PFAM: Rieske [2Fe-2S] domain protein; KEGG: fal:FRAAL5110 ubiquinol-cytochrome c reductase iron-sulfur subunit (Rieske iron-sulfur protein).
 
 
 0.999
ctaB
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
 
 
 0.998
atpB
ATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
  
 
 0.995
Afer_0375
KEGG: fre:Franean1_6082 proton-translocating NADH- quinone oxidoreductase, chain M; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I).
  
 
 0.994
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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