STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1837PFAM: protein of unknown function DUF75; KEGG: kra:Krad_1842 hypothetical protein. (284 aa)    
Predicted Functional Partners:
Afer_0695
PFAM: pyridoxamine 5'-phosphate oxidase-related FMN- binding; KEGG: fra:Francci3_4252 pyridoxamine 5'-phosphate oxidase-related, FMN-binding.
  
    0.804
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
     0.742
Afer_0459
TIGRFAM: IMP dehydrogenase family protein; PFAM: IMP dehydrogenase/GMP reductase; KEGG: rxy:Rxyl_0815 inositol-5-monophosphate dehydrogenase.
  
     0.672
Afer_0749
PFAM: bifunctional deaminase-reductase domain protein; KEGG: ace:Acel_1375 deaminase-reductase domain- containing protein.
  
     0.639
Afer_1784
PFAM: pyridoxamine 5'-phosphate oxidase-related FMN- binding; KEGG: mab:MAB_3296 hypothetical protein.
  
    0.631
Afer_0193
PFAM: cytochrome oxidase assembly; KEGG: fra:Francci3_1653 cytochrome oxidase assembly.
  
     0.622
Afer_1126
Transcriptional regulator, MerR family; PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: sma:SAV_6982 hypothetical protein.
  
     0.615
Afer_0723
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.590
Afer_1309
KEGG: mva:Mvan_4367 pyridoxamine 5'-phosphate oxidase-related, FMN-binding.
   
    0.567
Afer_1836
PFAM: GCN5-related N-acetyltransferase; KEGG: bpt:Bpet3221 acetyltransferase.
       0.554
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.