Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Afer_1850TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; trehalose-phosphatase; PFAM: trehalose-phosphatase; KEGG: saq:Sare_0810 HAD family hydrolase. (267 aa)    
Predicted Functional Partners:
Afer_1849
PFAM: glycosyl transferase family 20; KEGG: sco:SCO4290 trehalose-phosphate synthase.
 
 
 0.999
Afer_1778
KEGG: fal:FRAAL5900 trehalose synthase (maltose alpha-D-glucosyltransferase); TIGRFAM: trehalose synthase; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain.
 
 
 0.950
Afer_0495
PFAM: glycoside hydrolase 15-related; KEGG: ote:Oter_3331 glycoside hydrolase 15-related.
 
   
 0.778
Afer_0620
KEGG: mem:Memar_0869 hypothetical protein.
   
    0.736
Afer_1851
PFAM: regulatory protein TetR; KEGG: msm:MSMEG_5282 transcriptional regulator.
       0.668
Afer_0838
PFAM: MscS Mechanosensitive ion channel; KEGG: bcm:Bcenmc03_1911 MscS mechanosensitive ion channel.
 
   
 0.615
Afer_1848
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
       0.533
Afer_0360
KEGG: npu:Npun_F1793 amylo-alpha-1,6-glucosidase.
 
  
 0.488
Afer_1847
PFAM: thiamineS protein; KEGG: hya:HY04AAS1_0115 MoaD family protein.
       0.471
Afer_0384
RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: scl:sce8793 ECF family RNA polymerase sigma factor.
   
    0.424
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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