Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
moaCMolybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (163 aa)    
Predicted Functional Partners:
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
 
 0.999
Afer_1884
PFAM: molybdopterin biosynthesis MoaE protein; KEGG: mem:Memar_1334 molybdopterin biosynthesis MoaE.
 
 
 0.997
Afer_1686
TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: molybdopterin binding domain; KEGG: fra:Francci3_4037 molybdopterin adenylyltransferase.
  
 0.996
Afer_0486
Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
  
 0.962
Afer_0179
PFAM: thiamineS protein; KEGG: afw:Anae109_1160 molybdopterin converting factor, subunit 1.
  
  
 0.809
Afer_1847
PFAM: thiamineS protein; KEGG: hya:HY04AAS1_0115 MoaD family protein.
  
  
 0.809
Afer_1855
KEGG: lfe:LAF_1457 hypothetical protein.
       0.773
Afer_1097
PFAM: Indole-3-glycerol phosphate synthase; KEGG: bvu:BVU_4091 indole-3-glycerol-phosphate synthase; Belongs to the TrpC family.
    
 0.706
Afer_0728
PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; Rhodanese domain protein; SMART: Rhodanese domain protein; KEGG: mxa:MXAN_2588 molybdopterin biosynthesis protein MoeB.
 
   
 0.617
Afer_1933
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bvi:Bcep1808_7295 tungstate/molybdate transport system permease protein.
 
   
 0.584
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.