STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1874PFAM: class II aldolase/adducin family protein; KEGG: sth:STH188 sugar isomerase. (221 aa)    
Predicted Functional Partners:
Afer_1777
Citrate (pro-3S)-lyase; PFAM: HpcH/HpaI aldolase; KEGG: sgr:SGR_1172 putative lyase; Belongs to the HpcH/HpaI aldolase family.
   
    0.932
Afer_0165
KEGG: afw:Anae109_0447 ribulose-phosphate 3- epimerase; TIGRFAM: ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
     
 0.918
Afer_1875
PFAM: Carboxymuconolactone decarboxylase; KEGG: mmw:Mmwyl1_1812 alkylhydroperoxidase.
       0.805
Afer_1876
Transcriptional regulator, MarR family; PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: sen:SACE_7045 MarR family transcriptional regulator.
       0.803
Afer_0723
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
  
 0.693
Afer_0119
PFAM: ribulose bisphosphate carboxylase large chain; Ribulose bisphosphate carboxylase, large subunit- like; KEGG: afe:Lferr_1389 ribulose-bisphosphate carboxylase; Belongs to the RuBisCO large chain family.
  
  
 0.637
Afer_1877
Hypothetical protein.
       0.559
Afer_1872
Hypothetical protein; KEGG: sco:SCO5397 large Ala/Glu-rich protein.
       0.552
Afer_1873
Secreted protein containing a PDZ domain; KEGG: sen:SACE_1100 PDZ/DHR/GLGF.
       0.552
Afer_1871
PFAM: protein of unknown function UPF0182; KEGG: pth:PTH_1387 hypothetical protein.
       0.541
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.