Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1875PFAM: Carboxymuconolactone decarboxylase; KEGG: mmw:Mmwyl1_1812 alkylhydroperoxidase. (131 aa)    
Predicted Functional Partners:
Afer_1307
PFAM: alpha/beta hydrolase fold; KEGG: met:M446_4655 3-oxoadipate enol-lactonase.
    
 0.903
Afer_1874
PFAM: class II aldolase/adducin family protein; KEGG: sth:STH188 sugar isomerase.
       0.788
Afer_1876
Transcriptional regulator, MarR family; PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: sen:SACE_7045 MarR family transcriptional regulator.
       0.787
Afer_1877
Hypothetical protein.
       0.559
Afer_1872
Hypothetical protein; KEGG: sco:SCO5397 large Ala/Glu-rich protein.
       0.552
Afer_1873
Secreted protein containing a PDZ domain; KEGG: sen:SACE_1100 PDZ/DHR/GLGF.
       0.552
Afer_1871
PFAM: protein of unknown function UPF0182; KEGG: pth:PTH_1387 hypothetical protein.
       0.541
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
 0.525
Afer_0274
Transcriptional regulator, XRE family; PFAM: Cupin 2 conserved barrel domain protein; helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: art:Arth_0847 transcriptional regulator, XRE family with cupin sensor.
     
 0.419
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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